部分发表文章

Select Publications

1.  Zhou WZ, Ye AY, Sun Z, Tian HH, Pu TZ, Wu YY, Wang DD, Zhao M, Lu SJ, Yang CH, Wei L., Statistical analysis of twenty years (1993-2012) of data from mainland China’s first intervention center for children with Autism Spectrum Disorder. Molecular Autism. 2014, 5:52.

2.  Zhao HQ, Zhang P, Gao H, He X, Dou Y, Huang AY, Liu X, Ye AY, Dong MQ, Wei L. Profiling the RNA editomes of wild-type C. elegans and ADAR mutants. Genome Res. 2014 Nov 4. pii: gr.176107.114. [Epub ahead of print]

3.  Iossifov I, et al, The contribution of de novo coding mutations to autism spectrum disorder, Nature. 2014 Nov 13;515(7526):216-21. doi: 10.1038/nature13908. Epub 2014 Oct 29.

4.  Ding Y, et al, Wei L. "Bioinformatics: Introduction and Methods", a bilingual Massive Open Online Course (MOOC) as a new example for global bioinformatics education. PLoS Computational Biology, 2014, in press

5.  Dong S, Walker MF, Carriero NJ, DiCola M, Willsey AJ, Ye AY, Waqar Z, Gonzalez LE, Overton JD, Frahm S, Keaney JF 3rd, Teran NA, Dea J, Mandell JD, Hus Bal V, Sullivan CA, DiLullo NM, Khalil RO, Gockley J, Yuksel Z, Sertel SM, Ercan-Sencicek AG, Gupta AR, Mane SM, Sheldon M, Brooks AI, Roeder K, Devlin B, State MW, Wei L, Sanders SJ.. De novo insertions and deletions of predominantly paternal origin are associated with autism spectrum disorder. 购宝钱包 Rep. 2014 Oct 9;9(1):16-23. doi: 10.1016/j.celrep.2014.08.068. Epub 2014 Oct 2.

6.  Huang YA, Xu X, Ye AY, Wu Q, Yan L, Zhao B, Yang X, He Y, Wang S, Zhang Z, Gu B, Zhao HQ, Wang M, Gao H, Gao G, Zhang Z, Yang X, Wu X, Zhang Y, Wei L. Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals. 购宝钱包 Res. 2014 Nov;24(11):1311-27. doi: 10.1038/cr.2014.131. Epub 2014 Oct 14.

7.  Yang X, Gao H, Zhang J, Xu X, Liu X, Wu X, Wei L, Zhang Y. ATP1A3 Mutations and Genotype-Phenotype Correlation of Alternating Hemiplegia of Childhood in Chinese Patients.  PLoS One. 2014 May 19;9(5):e97274

8.  Gao G, Vibranovski MD, Zhang L, Li Z, Liu M, Zhang YE, Li X, Zhang W, Fan Q, VanKuren NW, Long M, Wei L. A long term demasculinization of X-linked intergenic noncoding RNAs in Drosophila melanogaster. Genome Res. 2014. Apr;24(4):629-38.

9.  Willsey AJ, et.al., Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism.  购宝钱包 . 2013 Nov 21;155(5):997-1007. doi: 10.1016/j.购宝钱包 .2013.10.020.

10. Huang Y, Xie C, Ye AY, Li CY, Gao G, Wei L. Recent adaptive events in human brain revealed by meta-analysis of positively selected genes.  PLoS One. 2013 Apr 9;8(4):e61280.

11. Xie C, Zhang YE, Chen JY, Liu CJ, Zhou WZ, Li Y, Zhang M, Zhang R, Wei L, and Li CY. Hominoid-specific de novo protein-coding genes originating from long non-coding RNAs.  PLoS Genet. 2012 Sep;8(9):e1002942.

12. Xu LM, Li JR, Huang Y, Zhao M, Tang X, Wei L. AutismKB: an evidence-based knowledgebase of autism genetics. Nucleic Acids Res. 2012 Jan;40(Database issue):D1016-22

13. Li CY, Zhang Y, Wang Z, Zhang Y, Cao C, Zhang PW, Lu SJ, Li XM, Yu Q, Zheng X, Du Q, Uhl GR, Liu QR, Wei L. A human-specific de novo protein-coding gene associated with human brain functions. PLoS Comput Biol. 2010 Mar 26;6(3):e1000734.

14. Zhang Y, Lu S, Zhao S, Zheng X, Long M, Wei L. Positive selection for the male functionality of a co-retroposed gene in the hominoids, BMC Evolutionary Biology. 2009. 9, 252

15. Gao G, Li JT, Kong L, Tao L, Wei L, Human herpesvirus miRNAs statistically preferentially target host genes involved in 购宝钱包 signaling and adhesion/junction pathways. 购宝钱包 Research. 2009 May;19(5):665-7

16. Li JT, Zhang Y, Kong L, Liu QR, Wei L., Trans-natural antisense transcripts including noncoding RNAs in 10 species: implications for expression regulation. Nucleic Acids Res. 2008 Sep;36(15):4833-44

17. Li CY, Mao X, Wei L, Genes and (Common) Pathways Underlying Drug Addiction, Plos Computational Biology, 2008, Jan 4;4(1):e2. (This work was featured by Science Signaling, the Economist, Reuters, and ~100 other scientific and public media.)

18. Kong L, Zhang Y, Ye ZQ, Liu XQ, Zhao SQ, Wei L, Gao G. CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine. Nucleic Acids Res. 2007 Jul 1;35:W345-9.

19. Ye ZQ, Zhao SQ, Gao G, Liu XQ, Langlois RE, Lu H, Wei L. Finding new structural and sequence attributes to predict possible disease association of single amino acid polymorphism (SAP). Bioinformatics. 2007 Jun 15;23(12):1444-50.

20. Li CY, Yu Q, Ye ZQ, Sun Y, He Q, Li XM, Zhang W, Luo J, Gu X, Zheng X, Wei L. A nonsynonymous SNP in human cytosolic sialidase in a small Asian population results in reduced enzyme activity: potential link with severe adverse reactions to oseltamivir. 购宝钱包 Res. 2007 Apr;17(4):357-62. (Cover story and featured by a Research Highlight. Highlighted by FDA annual Pediatric Safety Update for Tamiflu.)

21. Cai Z, Mao X, Li S, Wei L. Genome comparison using Gene Ontology (GO) with statistical testing, BMC Bioinformatics 2006, 7:374.

22. Shi YH, Zhu SW, Feng JX, Mao X, Zhang L, Cheng J, Wei L, Wang ZY, Zhu YX, “Transcriptome Profiling, Molecular Biological and Physiological Studies Revealed a Major Role of Ethylene in Cotton Fiber 购宝钱包 Elongation”,Plant 购宝钱包 , 2006 Mar;18(3):651-64.

23. Mao X., Cai T., Olyarchuk J.G., Wei L., “Automated Genome Annotation and Pathway Identification Using the KEGG Orthology (KO) As a Controlled Vocabulary”, Bioinformatics, 21(19): 3787–93, 2005

应邀综述

Invited Reviews

1. Wei L, Yu J. Bioinformatics in china: a personal perspective. PLoS Comput Biol. 2008 Apr 25;4(4):e1000020

2. Wei L, Liu Y, Dubchak I, Shon JCY, and Park JY, “Comparative Genomics Approaches to Study Organism Similarities and Differences.” Journal of Biomedical Informatics, 35:142-150, 2002.

专利

Patent

魏丽萍、李川昀、叶志强、贺权源、于泉、张武学、孙颖、罗静初、顾孝诚、郑晓峰， “一种预测达菲类药物用药安全性的方法”. 专利号ZL 200610011569.3. 专利申请日：2006-3-28. 授权公告日：2008-3-26.

Wei L, Li CY, Ye ZQ, He QY, Yu Q, Zhang WX, Sun Y, Luo J, Gu XC, Zheng XF, Chinese patent “A method to predict the safety of administering Oseltamivir Phosphate”. Patent Number: ZL 200610011569.3. Priority Date: March 28, 2006. Issued: March 26, 2008.