发表文章 Publications

(# corresponding author, * co-first author)

Key research papers:

1.       Zhong, S., Zhang, X., Gao, X., Li, Z., Huang, L., Guo, Q., Gong, R., Ren, J., Luo, M.^#, Lin, R.^#, (2025). Ultrabright Chemical Labeling Enables Rapid Neural Connectivity Profiling in Large Tissue Samples. Neuron 113 (22), 3741–3757 (Cover Story).

2.       Zhong, S., Wang, R., Gao, X., Guo, Q., Lin, R.^#, Luo, M.^#, (2025). Modular DNA Barcoding of Nanobodies Enables Multiplexed in situ Protein Imaging and High-throughput Biomolecule Detection. eLife 14:RP105225

3.       Lin, R.*#, Zhou, Y.*, Yan, T.*, Wang, R.*, Li, H., Wu, Z., Zhang, X, Zhou, X, F., Zhang, L., Li, Y., Luo, M.#, (2022). Directed evolution of adeno-associated virus for efficient gene delivery to microglia. Nature Methods, 19, 976–985.

4.       Lin, R.*#, Liang, J.*, Wang, R., Yan, T., Guo, Z., Liu, Y., Feng, Q., Sun, F., Li, Y., Li, A., Gong, H., Luo, M.#, (2020). The raphe dopamine system controls the expression of incentive memory. Neuron 106 (3), 498-514.

5.       Lin, R.*, Wang, R.*, Yuan, J.*, Feng, Q., Zhou, Y., Zeng, S., Ren, M., Jiang, S., Ni, H., Zhou, C., Gong, H., Luo, M., (2018). 购宝钱包 -type-specific and projection-specific brain-wide reconstruction of single neurons. Nature Methods 15, 1033–1036.

6.       Lin, R., Feng, Q., Li, P., Zhou, P., Wang, R., Liu, Z., Wang, Z., Qi, X., Tang, N., Shao, F., Luo, M., (2018). A hybridization-chain-reaction-based method for amplifying immunosignals. Nature Methods 15, 275–278.

Review papers:

1.       Lin, R.*#, Liang, J.*, Luo, M.#, (2021). The raphe dopamine system: roles in salience encoding, memory expression, and addiction. Trends in Neurosciences 44, 366–377.

2.       Liu, Z., Lin, R., Luo, M., (2020). Reward contributions to serotonergic functions. Annual Review of Neuroscience. 43, 141–162.

3.       Lin, R., Yan, T., Luo, M., (2019). The two faces of PVN CRF neurons. Nature Neuroscience 22, 508–510.

4.       Lin, R.#, Yi, L., Luo, M., (2018). A neural circuit driving maternal behaviors. Neuron 98 (1), 6-8.

Other research papers:

1.       Li, Z., Shang, Z., Liu, J., Zhen, H., Zhu, E., Zhong, S., Sturgess, R., Zhou, Y., Hu, X., Zhao, X., Wu, Y., Li, P., Lin, R., Ren, J., (2023). D-LMBmap: a fully automated deep-learning pipeline for whole-brain profiling of neural circuitry. Nature Methods 20, 1593–1604.

2.       Yuan, Z., Qi, Z., Wang, R., Cui, Y., An, S., Wu, G., Feng, Q., Lin, R., Dai, R., Li, A., Gong, H., Luo, Q., Fu, L., Luo, M., (2023). A corticoamygdalar pathway controls reward devaluation and depression using dynamic inhibition code. Neuron 111, 1–17.

3.       Feng, Q., An, S., Wang, R., Lin, R., Li, A., Gong, H., Luo, M., (2021). Whole-brain reconstruction of neurons in the ventral pallidum reveals diverse projection patterns. Frontiers in Neuroanatomy 15, 108.

4.       Lu, L., Ren, Y., Yu, T., Liu, Z., Wang, S., Tan, L., Zeng, J., Feng, Q., Lin, R., Liu, Y., Guo, Q., Luo, M., (2020). Control of locomotor speed, arousal, and hippocampal theta rhythms by the nucleus incertus. Nat Commun 11, 262.

5.       Ren, J.*, Isakova, A.*, Friedmann, D.*, Zeng, J.*, Grutzner, S., Pun, A., Zhao, G.Q., Kolluru, S.S., Wang, R., Lin, R., Li, P., Li, A., Raymond, J.L., Luo, Q., Luo, M., Quake, S.R., Luo, L., (2019). Single-购宝钱包 transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei. eLife 8, e49424.

6.       Zhao, Z., Wang, L., Gao, W., Hu, F., Zhang, J., Ren, Y., Lin, R., Feng, Q., Cheng, M., Ju, D., Chi, Q., Wang, D., Song, S., Luo, M., Zhan, C., (2017). A central catecholaminergic circuit controls blood glucose levels during stress. Neuron 95 (1), 138-152.

7.       Zhang, J., Tan, L., Ren, Y., Liang, J., Lin, R., Feng, Q., Zhou, J., Hu, F., Ren, J., Wei, C., Yu, T., Zhuang, Y., Bettler, B., Wang, F., Luo, M., (2016). Presynaptic excitation via GABA_B receptors in habenula cholinergic neurons regulates fear memory expression. 购宝钱包 166 (3), 716-728.

8.       Ren, J., Zhang, M.-J., Li, T.-M., Zhang, J., Lin, R., Chen, S., Luo, M., and Dong, M.-Q. (2016). Quantitative proteomics of sleep-deprived mouse brains reveals global changes in mitochondrial proteins. PLOS ONE 11(9): e0163500.

9.       Wang, D., He, X., Zhao, Z., Feng, Q., Lin, R., Sun, Y., Ding, T., Xu, F., Luo, M., Zhan, C., (2015). Whole-brain mapping of the direct inputs and axonal projections of POMC and AgRP neurons. Frontiers in Neuroanatomy 9, 40.

10.   Guo, Q., Zhou, J., Feng, Q., Lin, R., Gong, H., Luo, Q., Zeng, S., Luo, M., Fu, L., (2015). Multi-channel fiber photometry for population neuronal activity recording. Biomedical Optics Express 6 (10), 3919-393.

11.   Guo, Q., Wang, D., He, X., Feng, Q., Lin, R., Xu, F., Fu, L., Luo, M., (2015). Whole-brain mapping of inputs to projection neurons and cholinergic interneurons in the dorsal striatum. PLOS ONE 10(4): e0123381.